Nerivio uses electrical signals to calm down neurons during a migraine attack. These may include: Prescription medications, such as triptans or oral steroids. Find out the types, names, and ratings of 84 migraine medications, including abortive and preventive treatments. Grossman suggests about a cup to a cup and a half of coffee per day, with a daily maximum of 200 milligrams of caffeine. The gepants come as tablets and can be compared to the triptans in their role as an acute treatment, to treat a migraine attack. Nurtec ODT can be taken every second day to prevent episodic migraine. dizziness or feeling faint. · Coenzyme Q10: 100mg 3× per day. Mar 9, 2022 · Blood pressure medications: Beta blockers, such as propranolol and metoprolol, can help with migraine prevention. A migraine is a headache that can cause severe throbbing pain or a pulsing sensation, usually on one side of the head. Antimigraine agents are used to treat migraine headaches. · Vitamin B2(Riboflavin): 400 mg per day. As a preventive medication for migraine, antidepressants can take 4 to 6 weeks or more to show benefits. Numbness and tingling in the body. Light and sound can make migraine pain worse. Pregnancy-Safe Preventive Migraine Treatment Options Cyproheptadine Verapamil Memantine Feb 2, 2023 · The goal of preventive treatment for migraine is to reduce the frequency, severity, duration and disability of attacks, and improve response to and minimize use of acute medications. Two of these types of medications are FDA approved for migraine prevention Aug 28, 2023 · Depakote and sodium valproate are two anticonvulsant drugs used for migraine prophylaxis. Antiemetics. Call your healthcare provider or get emergency medical help right away if you have any symptoms of an allergic reaction: rash; swelling of your face, lips, tongue, or throat; if you have trouble breathing Nov 21, 2023 · A drug’s mechanism of action is how the drug works. Nurtec ODT was initially approved for acute use—to treat an existing migraine—in February of last year. Triptans - eg, almotriptan, naratriptan, sumatriptan, zolmitriptan. VYEPTI is a prescription medicine used for the preventive treatment of migraine in adults. Anti-sickness medicines - eg, domperidone, prochlorperazine. Turn off the lights. Anti-seizure drugs. The following are most commonly recommended for migraine: · Magnesium Citrateor Glycinate: 300 mg 2× per day. Feb 15, 2018 · Am Fam Physician. This medication is used to prevent or treat migraine. Triptans. Not all beta blockers should be used for migraine prevention. Several oral medications were developed to treat other health conditions—high blood pressure, seizure, and depression—but were later found to help prevent migraine attacks. 4, 38, 39 Their proposed mechanism of action is thought to involve the inhibition of central cortical depression and sympathetic activity associated with migraine pathophysiology. A warning: should any drug that treats epilepsy, high blood pressure, or depression be used for migraine «just in case it works»? Some tables online list many other drugs, especially blood pressure and depression medications that some physicians may use but have not been studied specifically for migraine. Topiramate (Topamax®) is a commonly used anticonvulsant for migraine prevention. Beta-blockers are Apr 18, 2024 · Aimovig (full biological name erenumab-aooe) is a once-monthly, injectable medication that can be self-administered subcutaneously (under the skin) for the prevention of migraine in adults. They stop or reduce migraine symptoms like pain, nausea, sensitivity and more. Whether you have lived with migraine for a few months or a few decades, you know migraine can be a challenging experience. You should be careful. Common side effects include nausea, drowsiness, hair loss, tremors, and hyperammonemia. Nausea may be a side effect from these medications and also Mar 11, 2018 · In addition to the medications approved for Migraine prevention, the FDA has also approved onabotulinumtoxinA (Botox) for the treatment (prevention) of chronic Migraine. Among other Jan 11, 2024 · Drugs originally developed decades ago to treat epilepsy (like topiramate), high blood pressure (like propranolol), and depression (like amitriptyline) have been used to prevent migraines for years. Just to name a few. May 10, 2024 · Standard treatments taken at the onset of a migraine episode (also called acute or abortive treatment) include oral medications, such as: over-the-counter analgesics (pain relievers), such as Mar 31, 2023 · Prescription Analgesics. There have been Acetaminophen or aspirin combined with caffeine, barbiturates or codeine and oxycodone. That means triptans are most effective if taken at the start of a migraine. Addressing lifestyle triggers and comorbidities in patients with migraine can be particularly beneficial for patients. It is important for the clinician to recognize that most antiepileptic drugs may substantially interfere with the efficacy of oral contraceptives, with the Nov 2, 2018 · 929-376-1333. Jun 29, 2024 · There are four types of medicines that are commonly used to treat migraine attacks: Ordinary painkillers - eg, paracetamol. According to experts, there are now many medications and products available to help people prevent their migraines. Apply hot or cold compresses to your head or neck. Jun 28, 2022 · This is a growing class of drugs. Examples of SNRIs used to treat migraine include: 2. Jul 5, 2024 · The abortive (symptomatic) therapy of migraine ranges from the use of simple analgesics such as nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen to triptans, antiemetics, calcitonin gene-related peptide (CGRP) antagonists, lasmiditan, and dihydroergotamine. Learn more about the types, causes, symptoms, diagnosis, & treatment of migraines. A newer antidepressant that made it to the preventive list is venlafaxine, which helps with mood and does not result in weight gain. CGRP inhibitors were the first drugs to be specifically developed for migraine prevention. Common side effects include headache, neck pain, and pain at the injection site. Jun 14, 2021 · The FDA has approved the first drug that can both treat and prevent migraines. Is characterized by symptoms that can affect the senses. Rimegepant may work by changing the amount of a certain natural substance in the brain. The first CGRP for migraine prevention was approved in 2018. Unlike the medications discussed above, it’s not used to prevent migraines. Topamax and Depakote are both FDA-approved to prevent certain types of seizures, as well as prevent migraine. They should be taken at the start of an attack, as early as possible, to treat pain and associated migraine symptoms (e. After triptans, the next most helpful drug classes were ergots such as dihydroergotamine (Migranal, Trudhesa) and anti-emetics such as promethazine (Phenergan). May 12, 2023 · Other Treatments. Scientists Feb 9, 2023 · CGRP inhibitors were the first class of drugs developed to prevent migraines with or without visual auras. CGRP injections can cost $7,000 each year. You and your healthcare provider can decide which drug you should take and in what form. Sep 21, 2016 · There are currently several different formulations of ergotamine for the acute treatment of migraine including oral, rectal, or intranasalDihydroergotamine is available as an intranasal, intramuscular, or intravenous treatment. Comparing CGRP blockers is the next big challenge for Migraine patients. In fact, if you give CGRP by an intravenous method to a person with Caffeine: Many women decide to cut out caffeine completely when they become pregnant, but a low level of caffeine is considered safe and can help prevent migraine. You should not take more than 1 tablet in 24 hours. In contrast, aura: Typically lasts five minutes to one hour. In a big win for the migraine community, fremanezumab (AJOVY™), was recently approved by the FDA for the treatment and prevention of migraine. Common side effects are lethargy, depression, exercise intolerance, hypotension and sleep disorders. These medications, include Ubrelvy (ubrogepant), Nurtec (rimegepant) and Atogepant (Qulipta). this resource. S. Dr. Over-the-counter (OTC) pain medications are often used to ease symptoms of a migraine attack that’s already begun. It’s quite common for medications to be prescribed for Jan 10, 2024 · For prevention of migraine headaches: Emgality is usually given as a first dose of 2 injections, followed by 1 injection once per month. Improve responsiveness to treatment of acute attacks. Antiepileptic drugs are increasingly recommended for migraine prevention because of well-conducted placebo-controlled trials (Table 2-4). Jun 17, 2024 · Anti-seizure drugs (anticonvulsants), such as Depakote ( divalproex sodium) or Topamax ( topiramate ), may be used to prevent migraine attacks. Prevention does not always involve a medicinal drug. If you are having at least four migraine attacks per month you may wish to discuss preventive medication with APPROVED USE. Mar 9, 2019 · Bayer Aspirin, Bufferin, Ecotrin, and Zorprin. Abortive medications are known as Triptans. Migraines are different from other headaches because they occur with symptoms such as nausea, vomiting, or sensitivity to light. For years, people who experience migraine Supplementation is intended to reduce the frequency or intensity of your monthly migraine attacks. Pain relieving drugs can be taken as soon as the pain May 8, 2023 · Amitriptyline is an old, inexpensive medication that effectively prevents episodic migraine. Although many patients benefit from lifestyle modifications — including attention to sleep hygiene, exercise and diet, maintaining a headache diary, and using Jun 7, 2024 · Nerivio Armband Device. It’s an oral tablet that should be taken with a glass of water and swallowed whole. Qulipta (atogepant): Approved Sept 28, 2021. Tricyclic Agents . The medications can be used along previous first-line treatments for migraine. pain on one side of your head, either on the left side, right side, front, or back, or in your temples. Migraine is a primary headache disorder characterized by recurrent attacks. Patients on propranolol who take eletriptan acutely to These include eating regular, healthy meals, adequate sleep, and at least one half hour of exercise (walking is fine) per day. While these options cannot typically relieve the pain of an active migraine, they do work to prevent migraine onset. Certain medications, such as CGRP antagonists and beta blockers, may be recommended to prevent migraine. They are taken every day and are aimed at preventing migraine attacks altogether or at least reducing their frequency and severity. Read this articleMove Against Migraine support group. These are funded and prescription only. There are two main categories of drugs for managing migraine headaches: those taken to prevent them from happening and those used for the acute treatment of a migraine that's already underway. This class of medications is used to treat cardiovascular conditions such as high blood pressure. Treatment of chronic migraine includes preventive treatments such as Botox (onabotulinumtoxinA), the calcitonin gene-related peptide (CGRP) antagonists, and medicines used for the acute treatment of migraine such as analgesics, triptans, and oral gepants. Jan 18, 2024 · Beta-blockers are a preventive first choice for migraine. american migraine foundation 1177 6th avenue, 5th floor New York, NY 10036. It is recommended for people with migraine aura. TCAs used to treat migraine include: 2. Migraine is a common type of primary headache disorder. Mar 14, 2024 · Migraine headaches, also known as migraines, are a type of headache that can cause debilitating pain. When CGRP is released, it causes intense inflammation in the coverings of the brain (the meninges), and for most migraine patients, causes the pain of a migraine attack. Some people who get migraines have warning symptoms, called an aura, before the actual headache begins. Medications for Migraine Prevention. Antidepressants. The drugs that are FDA approved for migraine prevention include: erenumab (Aimovig) fremanezumab (Ajovy) galcanezumab (Emgality) eptinezumab (Vyepti) atogepant Jan 28, 2021 · DHE is a fast-acting, effective way to treat a migraine attack and has a couple of benefits over other forms of treatment. The most common is a type of drug called tricyclic antidepressants (TCA). Visual disturbances (such as “stars” or “lightning”) Temporary loss of sight. VYEPTI may cause allergic reactions. Studies show that both drugs are effective and well-tolerated. Magnesium: Magnesium is a supplement commonly used for Antiepileptic Drugs for the Prevention of Migraine. My research for a list of migraine medications uncovered over 100 different ones available on prescription. New, promising treatment options are coming out, and these breakthroughs offer hope for better migraine symptom relief and prevention. Lasmiditan (Reyvow) Dihydroergotamine. Sep 8, 2023 · Costs of injectable migraine medications. Avoid their use in patients with asthma, diabetes, bradycardia and congestive heart failure. The headache is usually unilateral, pulsating, aggravated by routine physical activity, and may be severe enough to Jan 30, 2023 · increased sensitivity to light and sound. Food and Drug Administration today approved Aimovig (erenumab-aooe) for the preventive treatment of migraine in adults. Migraine Treatment. Avoid their use in patients with asthma, diabetes, bradycardia and congestive heart Introduction. Injectable drugs for migraine prevention can be costly without insurance coverage. some types of alcohol, cheese, oranges and chocolate), dehydration and caffeine overuse are important to recognise and manage. Maintain cost of care for migraine treatments. For example, DHE has low rates of a migraine attack returning within 24 hours after relief from the initial attack. The tables below contain preventive migraine treatment options that are safe in pregnancy as well as preventive options to avoid during this time. Instead, these medications help relieve symptoms by shrinking swollen blood vessels in the brain that develop from migraine attacks. Common side effects are lethargy, , exercise intolerance, hypotension, depression, and sleep disorders. Migraine attacks can last for hours to days, and the pain can be so bad that it interferes with your daily activities. CGRP therapies for migraine prevention Dec 20, 2022 · One kind, injectable medications, can both stop and prevent migraine episodes. 4. Nov 28, 2016 · The ultimate goals of migraine preventive therapy are to: Reduce frequency, severity, and duration of attacks. The various categories of preventive medication are: β-Blockers. Historically, the only therapies available were medications used for other diseases, such as seizure disorder, depression or high blood pressure, Nye says. May 13, 2020 · The most effective treatment for a migraine will depend on the individual and the severity of their symptoms. Oct 11, 2021 · This is an exciting time for people with migraine. Migraine Prevention. When a pregnant woman does get a migraine, there are as-needed medications that are considered likely to be safe. Preventive treatments for migraine aim to reduce the frequency, severity, and duration of migraines. Some of these medications are not safe to take during pregnancy. It occurs more commonly in females than in males, and is characterised by recurrent attacks of typically moderate to severe headaches that usually last between 4–72 hours. CGRP Antagonists. Nurtec ODT (rimegepant sulfate): Approved Feb 27, 2020. The ones approved for migraine prevention are: Metoprolol. Nov 23, 2022 · These medications are most commonly used to control blood pressure. Monoclonal antibody CGRP blockers are the first class of drugs specifically produced to prevent migraines. In addition to treating depression, antidepressants—such as amitriptyline and venlafaxine—can be an effective preventive treatment for migraine. Nerivio is used for acute relief and preventive treatment of migraine attacks in adults and adolescents 12 and older. Apr 27, 2023 · Official answer. When looking at OTC options, it’s important to also look at the active ingredients. Nov 16, 2021 · Beta-blockers. Botox (onabotulinumtoxinA) is FDA approved for the preventive treatment of chronic migraine. Migraine preventive therapy is indicated for patients with 4 or more migraine headache days per month, significant disability associated with individual attacks, or frequent acute medication use. The ones most often prescribed include: 1,3. The treatment is given by once-monthly self Jun 29, 2022 · difficulty concentrating. In addition to injectable CGRP antagonists, there are several other ways to prevent and treat migraine headaches. Nurtec ODT treats or helps prevent migraine by blocking the actions of a protein called calcitonin gene-related peptide (CGRP). Buprenorphine Codeine Fentanyl Hydromorphone Morphine Tramadol Oxycodone. Interestingly, the products sold as Excedrin® Migraine and Excedrin® Menstrual contain Apr 3, 2024 · CGRP inhibitors have been elevated to a first-line prevention method for migraine, according to the American Headache Society. The U. There are many other medications (more than 100 total) that are being used effectively for Migraine prevention. Learn about the drug classes, dosage, interactions, side effects, and more. Triptans are available as tablets, injections and nasal sprays. The newest novel drug (approved March 9, 2023) for the treatment of migraine is Zavzpret (zavegepant) nasal spray. Experts recommend their use for those with 6 or more migraine days per month, or when Sep 20, 2018 · Certain anticonvulsants (anti-seizure medications) can prevent migraine. And Nurtec can be used for both. Even if you take migraine medication, you should follow this program. Options include: Oct 31, 2022 · Four injectable medications are currently available for migraine prevention: Erenumab (Aimovig): This once-a-month injection is given into the subcutaneous tissue of your body, such as your abdomen, thigh, or upper arm. Fiorinal Tylenol 1,2,3,4 Anacin Oxycocet Percocet Tramacet. The safety of using more than 18 doses in a 30-day Jul 8, 2024 · It is not used to prevent migraines. Oct 1, 2018 · Understanding fremanezumab (AJOVY™), the latest FDA-approved treatment for migraine. Over-the-counter (OTC) medications, such as non-steroidal anti-inflammatories (NSAIDs) and acetaminophen. It helps to relieve headache, pain, and other migraine Mar 4, 2018 · Numerous issues can prevent people from using prescription migraine medications. Aimovig works by blocking the effect of calcitonin gene-related peptide (CGRP) which is a small protein that is highly prevalent in the sensory nerves that Feb 13, 2023 · Other Antidepressants Used in Headache Prevention 2 min read Along with traditional headache medications , other drugs -- like antidepressants -- can help you have fewer and less-severe headaches . Triptans may be taken as oral tablets, nasal sprays, or injections under the skin, which affects how quickly they work. Oct 1, 2020 · Management approach. Botox may cost up to $600 Jul 7, 2023 · Show transcript. , birth control pills) and addition of migraine-preventive medication may be advisable. Try temperature therapy. Prevention May 17, 2018. 1. Sleep if you can. those changes aren’t working, there are also preventive medications and treatment options to consider. Jan 25, 2023 · We would like to show you a description here but the site won’t allow us. [14] They are among the first-line agents used for migraine prevention. Español. More InfoSee Prices. Sep 7, 2023 · Last updated by Migraine & Headache Australia team on 7 September 2023. There are a variety of medications available for the acute treatment of migraines, however the same treatment may not work for every patient. Medications to prevent migraines: A healthcare provider usually prescribes preventive medications if you experience severe symptoms that interfere with your routine or have Mar 14, 2024 · Migraine headaches, also known as migraines, are a type of headache that can cause debilitating pain. The most common version of Maxalt is covered by 71% of insurance plans at a co-pay of $60. May work on more than just activated pathways in migraine. pulsing and Sep 10, 2020 · Dizziness, fatigue and nausea are common side effects. Behavioral treatment for stress reduction such as relaxation training, biofeedback, and yoga may be helpful. 2002;66 (11):2123-2130. 00, however, some pharmacy coupons or cash prices may be lower. Preventive medicines (also known as prophylactics) for migraine are taken to prevent migraine attacks. Without this program, migraine-preventive medication may not work to its full potential. Reduce excessive overuse of acute medications. Botulinum toxins are injected to prevent migraine in people with 15 or more headache days each month. It is available in generic and brand versions. Abortive medications are used to help prevent the attack from progressing. The newest drug (approved September 28, 2021) for the prevention of migraine (episodic migraine) is Qulipta (atogepant). It is a device that is attached to the upper arm and controlled via a smartphone. It also has a lower risk of medication overuse headache, making it a good option for patients with very Feb 5, 2024 · The researchers looked at 25 medications from seven drug classes to see which were most helpful for easing migraines. The Food and Drug Administration approved the most recent, atogepant (Qulipta), in September 2021. Researchers observed that 88% (185 / 211) patients did not have a migraine the day after taking a Qulipta 60 mg dose, compared to 75% (151 / 202) taking an inactive placebo pill. The selection of a specific agent depends on patient-specific factors May 25, 2020 · Migraine prevention is an important part of any individual’s treatment plan if they are experiencing frequent and disabling attacks. Ubrelvy is used to help treat acute migraines, while Qulipta is used for migraine prevention. For this study, researchers used national register data from 2010 to 2020 that included more than 100,000 people with migraine. Dec 1, 2023 · Anti-nausea drugs (such as chlorpromazine, metoclopramide, or prochlorperazine) may also be given with pain medications for migraines with aura accompanied by nausea and vomiting. Let’s cover injections for migraine — their types, mode of administration, side effects, and other helpful info Jan 17, 2024 · Over the past five years, however, new therapies have emerged that are changing the way migraine is managed. Jun 7, 2024 · A doctor may prescribe a beta-blocker, anticonvulsant, CGRP therapy, or other treatment to reduce the frequency, duration, and severity of migraine symptoms. Acute migraine medications are used at the onset of a migraine attack to reduce the symptoms associated with migraine. 40, 41 Mar 17, 2022 · Involves symptoms such as mood changes, muscle stiffness, food cravings and fatigue. Dec 15, 2023 · Ubrelvy (ubrogepant) was the first FDA-approved oral CGRP medication (“gepant”) for migraine treatment. Nortriptyline. Propranolol. It is slightly more popular than comparable drugs. Calcium channel blockers (a type of high blood pressure medicine) Beta blockers (a type of heart medicine) Certain antidepressants. They are particularly useful for prolonged and atypical migraines. Migraine abortives are medications taken after a an attack starts - usually at the first sign of aura. Although various classes of antidepressants have been studied and used to prevent migraine headache, more data are available for the tricyclic antidepressants (TCAs) (Table 1). Ubrelvy is approved to treat migraines in adults. com. Beta-blockers. New Migraine Medications; Acute Treatment Strategies; Medications for Migraines: What Else You Need to Know; Use Migraine Meds That Have Been Through Randomized Controlled Clinical Trials. Prevention may involve lifestyle modifications, injectables such as Botox or anti-CGRP antibodies, neurostimulation devices and complementary or alternative Instead, the drugs are used as an acute treatment. Opioids Short acting Long acting *** DANGER of chronification and side effects. These can help if your migraine with aura is accompanied by nausea and vomiting. Sleep disorders, dietary triggers (e. Propranolol, nadolol, atenolol, metoprolol and timolol are effective for migraine prevention. 00-$80. Now that we have three new preventive options specifically designed for Migraine, we’re faced with that all-important question: Which one should we choose: Aimovig, Ajovy, or Emgality? There are hundreds of drugs and supplements used for migraine prevention. Feb 27, 2023 · A migraine preventive medication aims to reduce the number and severity of your migraine attacks and improve your daily functioning and quality of life. g. Jul 2, 2021 · Anti-nausea drugs. Zavzpret (zavegepant) (intranasal/oral): Approved March 10, 2023. These are usually taken with pain medications. For treatment of cluster headache episodes: Emgality is usually given as 3 injections at the start of the cluster period, followed by 1 injection once per month until the end of the cluster period. Apr 13, 2023 · The following have been approved to date: Ubrelvy (ubrogepant): Approved Dec 23, 2019. While it can help with sleep and mood, it can result in weight gain, sedation and dry mouth. Methysergide. May 1, 2020 · Migraines are common, with a prevalence of 1% to 3% in children three to seven years of age, 4% to 11% in children seven to 11 years of age, and 8% to 23% in those 15 years of age. May 31, 2023 · Qulipta can begin working on the first day of treatment to help prevent your episodic migraine headaches. Some gepants can also be used as a preventive Atogepant is designed to be taken daily to prevent both chronic migraines (occurring more than 15 times a month) and episodic migraines (occurring between four and 15 times a month). Though these remain viable and effective options, some are not safe for older . nausea. It’s not clear why beta blockers work for migraine prevention, but research suggests they affect nerve cell communication in the brain. Amitriptyline. by Drugs. Corticosteroids. Valproic acid, gabapentin. increased heart rate. Other indications for preventive therapy are unusual migraine type at any frequency, (eg, brainstem aura or hemiplegic migraines), and May 25, 2018 · CGRP stands for calcitonin gene-related peptide, and it is a protein that is released around the brain. You or a caregiver will be trained to administer the injection at home using a prefilled syringe or autoinjector, a spring Jul 15, 2021 · OTC medications range from single ingredient medications like aspirin, acetaminophen, ibuprofen or naproxen sodium to combination medicines like Excedrin® Migraine. Reduce level of disability. When these circumstances arise, many turn to non-pharmacological approaches to migraine management. The angiotensin II receptor blocker candesartan has also been shown to Aug 8, 2023 · It is not known if it is safe to take Nurtec ODT for more than 15 migraine headaches in 30 days. Resources for migraine prevention, treatment, and symptom management. In most cases, one drug will have a number of Mar 10, 2021 · A variety of medications can be used to treat or prevent migraine. In a significant development, the American Headache Society (AHS) has Oct 4, 2022 · At the first sign of a migraine, take a break and step away from whatever you're doing if possible. Relax in a dark, quiet room. It's often accompanied by nausea, vomiting, and extreme sensitivity to light and sound. People with migraine usually take medication for their active migraine attacks, and some people also take medication to prevent future attacks. There are too many brands and forms of aspirin to list here. nausea, light/noise/smell sensitivity). Another type of antidepressant that may be used to treat migraines is called a serotonin and norepinephrine reuptake inhibitor (SNRI). Anti-nausea drugs include chlorpromazine, metoclopramide (Reglan) or prochlorperazine (Compro). Healthy body weight and exercise are In such cases, avoidance of certain other medications (e. Nurtec ODT can be taken once a day as needed, to treat an acute migraine. Apr 15, 2021 · Triptans cannot prevent a migraine attack from happening. The latter help ease nausea, another common migraine symptom. Health Conditions; Discover; We go over the types of migraine prevention medications and their pros and cons, from beta Feb 13, 2023 · Get an overview of medications, supplements, and lifestyle changes for migraine prevention, including the costs and use during pregnancy. Used for: to reduce fever and inflammation, colds and flu’s, headaches, and at 325 mgs has had good results with migraine incidence in men. Jan 23, 2024 · Medications to stop migraines: You can take these medications at the first sign of a migraine. Anti-inflammatory painkillers - eg, aspirin, ibuprofen. On the other hand, triptans, NSAIDs, and ergot alkaloids may be more effective for the acute treatment of migraines. 2018 was a landmark year for this new class of treatments specifically designed for migraine. Acetaminophen, nonsteroidal anti-inflammatory drugs, triptans, antiemetics Oct 3, 2018 · Last updated: Dec 22, 2019 @ 12:08 am Medical Review: David Watson, MD. ol zr or cv yc wk mq ov dq oh